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In both the B16F10 melanoma and E.G7-OVA lymphoma model, TDLN-targeting nanoparticle (NP)-conjugate vaccines induced substantially stronger local and systemic cytotoxic CD8+ T-cell responses when compared to non-TDLN-targeting vaccination, leading to enhanced tumor regression and host survival (237)

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But Kennedy, the chemical biologist, says this logic doesn't necessarily mean they will be safe when injected in higher doses and then circulated in the bloodstream, "potentially reaching other places they couldn't normally access." "Even if it may have anti-inflammatory properties as injected into your knee and we see some reduced swelling there, if it causes liver failure, it's a concern, right