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Materials and methods Animal models and fractionation Fmr1 (stock #003025, MGI:1857169) and Cntnap2 knockout (stock #017482, MGI: 2677631) mouse models and the BTBR+ (stock #002282), B6129SF2/J (stock #101045), and C57BL/6J (stock #000664) mouse strains were purchased from the Jackson Laboratory

doi: 10.1097/MOG.0b013e32830edc1e

Relat, J

Interestingly, in 4 of 5 subjects, the early antibody response was primarily directed towards the Fc domain, but over time, shifted to primarily recognize the Fab domains ( Figure 4B )

Patients can receive treatment as many as two times per week or as few as twice per month