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95 Similarly, the photosensitizer, NPe6, was reported to cause the immediate disruption of lysosomes, cathepsin-mediated cleavage of proapoptotic Bid, release of cytochrome c, and apoptosome activation after laser irradiation
doi: 10.1016/0035-9203(87)90032-0 145 LewisFAStirewaltMASouzaCPGazzinelliG
Replacing the spacer sequence with a functioning intron region enhanced the number of independently silenced lines from roughly 50 to over 100% [174]
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10.3390/nu9090980 163
