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Only mild toxicities induced by figitumumab have been reported [124]

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Inflammasomes activate Caspase-1, interleukin (IL)-1, and IL-18 to produce pyroptosis that releases damage-associated molecular patterns (DAMPs) to subsequently recruit more immune cells to mount a robust immune attack against pathogens 102

[DOI] [PubMed] [Google Scholar] 106.Ma N., Tian Y., Wu Y., Ma X