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The N-methyl-D-aspartate (NMDA) receptor plays a central role in this process

ESRD, End-Stage Renal Disease

Nuclear respiratory factors 1 and 2 (NRF1/NRF2) are transcription factors encoded in the nucleus signaling more than 250 genes
Autophagy is also enhanced by nutrient deprivation in the microenvironment, which activates FOXO3

3.3: Carsten Berndt, Leonie Thewes

Brigelius-Flohe R, Traber MG
