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More importantly, exercise-based therapy to reduce body weight for the treatment of KOA is consistently recommended in treatment guidelines [9]

SCFAs constitutes a direct linkage between gut microbiome and immune system due to their capability for inducting regulatory T-cells (Treg) [72] and regulating Tregs and Th17 balance [73]

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High mobility group box 1 mediates TMAO-induced endothelial dysfunction

A., Krauss, R
