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The FDA has approved more than 100 peptide-based drugs over the decades, including GLP-1 medications like semaglutide, which millions of people now take for weight loss

In the past, classical biochemical methods, such as cross-linking, gel filtration, native gel, and analytical ultracentrifugation (AUC) [130,131], have been used for determining the oligomeric state of PFPs [132,133,134]

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