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Figure 2 3.1 Receptor-mediated signaling pathways EEDs primarily compromise reproductive function by interfering with nuclear hormone receptor systems and membrane-associated signaling cascades that orchestrate normal reproductive physiology

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Moreover, TSA reduced cardiac hypertrophy in SHRs by inhibiting the Cys-C/Wnt signaling pathway, decreasing protein expression of Cys-C, Wnt2, -catenin and WISP-1 (107)

Brand-name somatropin costs $800-$3,000+ per month at therapeutic doses through pharmacy channels, driven by complex manufacturing (recombinant protein production) and pharmaceutical distribution overhead

NF-kappaB-mediated anti-inflammatory activity of the sesquiterpene lactone 7-hydroxyfrullanolide