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However, only low L-carnitine concentrations were found intra- and extracellularly (Figure 6B), suggesting that the biosensor is sensitive to low intracellular L-carnitine levels and that the export of L-carnitine out of the E

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Lipid overaccumulation leads to aberrant activation of mammalian target of rapamycin C1, causing macrophage 1 polarisation and elevating levels of CCL2, CCL5, IL-1, IL-6, inducible nitric oxide sythase and TNF-