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J Physiol Pharmacol, 60(Suppl 7), 115-122

Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain
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A healthy human body, on the other hand, can synthesize enough -lipoic acid to scavenge reactive oxygen species and increase endogenous antioxidants

Under hypoxic conditions, HIF-1 promotes PD-L1 upregulation, reinforcing immune evasion through both metabolic and immunoregulatory mechanisms [84]
