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The only interaction with the sulfonamide group is V127

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Lack of insulin receptor signaling in Leprechaunism may result in the rare event of an alive but severely small for gestational age baby that will only survive if treated with recombinant-IGF-1 to substitute inulin receptor signaling with IGF1R signaling via their common intracellular pathways
[DOI] [PMC free article] [PubMed] [Google Scholar] 110.Nicoliche T., Bartolomeo C.S., Lemes R.M.R., Pereira G.C., Nunes T.A., Oliveira R.B., Nicastro A.L.M., Soares .N., da Cunha Lima B.F., Rodrigues B.M., et al

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doi: 10.1007/s00125-009-1495-4 201 LeeCXiaoZLimIWangTAghaeiPBurkePJet al
