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[10] [4] Patients should contact their GP if they experience persistent or severe side effects, signs of allergic reaction (facial swelling, difficulty breathing, severe rash), or if symptoms of B12 deficiency (such as neurological symptoms, severe fatigue, or glossitis) do not improve after several weeks of supplementation

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discomfort is minimal and temporary

Nutritional deficiencies, particularly deficiencies in vitamins B1, B6 and B12 can damage nerves and cause neuropathy in feet and legs

How B12 and each of the biomarkers are affected, depends on which stage of B12 deficiency the individual is in

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