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The double membranes structure of mitochondria provides an ideal location for ferroptosis, and some researchers have observed mitochondrial impairment in patients with ferroptosis (Sha et al., 2021)

Western Blot Proteins from lipid rafts (5 ug), whole cell lysate (20 ug), or nuclear fractions (20 ug) were heated at 75C under denaturing conditions and resolved on 4-20% gradient gels

259 Moreover, the loss of the mitochondrial ABC transporter ATM1, which transports intermediates required for FeS cluster formation, exacerbates Cu-induced toxicity

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