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Therefore, neuronal subsets (iSPNs) from mouse striatal tissues of mutants and controls (here called iSPN + mut and iSPN + wt populations, respectively) were genetically labelled in vivo with a fluorescent marker using Rosa26-Ai9-tdTomato strain 21 and purified by fluorescence-activated cell sorting

References 1 Al Amin, A

All data were analyzed using SPSS 23.0 software (IBM Corp., Armonk) and Graphpad Prism 5.0 (GraphPad Software)

Structural characterization further demonstrated that FSEN1 interacts with a critical phenylalanine residue that is absent in mouse FSP1, explaining the human-specific activity of FSEN1

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