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Sometimes this issue is fixed simply by optimizing buffers, for instance by increasing salt or detergent concentration, so that the interacting protein no longer binds to the GST only control, but still binds to your GST-fusion protein of interest

M.Pereira MenezesS.Matos LimaE.Peres GramachoK.Silva AndradeB.Macdo FerreiraM.et al

Furthermore, the virus particle categorically hijacks vital human factors for its cell surface binding, host invasion, and viral RNA integration with human DNA

These results demonstrated that T7-LDL is an important potential drug delivery system for glioma-targeted therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Ilic S, Drmic D, Franjic S, Kolenc D, Coric M, Brcic L, et al

What they did: Two parallel series of experiments