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Although the hypersegmented neutrophils support the diagnosis of megaloblastic anaemia, they are not specific

A specific role for IGF-1 receptor (IGF-1R) signaling in the mediation of mammalian longevity was first established in IGF-1R haploinsufficient mice, which lived 33% longer than controls, but unlike other models of reduced somatotropic signaling, this effect was female specific 6

it is brought on by a lack of vitamin B12 in the diet or poor absorption

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TAM: F (1,21) = 15.23, p = 0.0008

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