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Taken together, our data demonstrate that USP7 stabilizes GATA1 by preventing its proteasomal degradation
Generally, these new strategies should be directed towards diseases with significant unmet clinical needs, including cases that have relapsed or are resistant to current treatments, as well as rare (orphan) diseases
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Still, early medical evaluation matters
However, the behavior can sometimes be more complex than linear (see Figure 2)
NAC, N-Acetyl-L-cysteine
