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Its primary job is to neutralize free radicalsunstable molecules that can cause oxidative stress

and actually SARS-CoV-2 causing COVID-19, all are characterized by persistent inflammation, continuous production of reactive oxygen/nitrogen species and oxidative stress that predominate over the antioxidant defenses (GSH and free radical scavenger enzymes) resulting in cell/tissue/organ aging associated with early (premature) chronic inflammation/inflammaging. We propose that, although inflammaging was introduced for the aging process (276289), it could also apply to early (premature) tissue and organ aging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses, especially low GSH levels, in younger individuals

Additional factors contribute to the differences between men and women, such as the increased risk women face due to certain characteristics

In preclinical models, the proposed mechanism most often discussed centers on actin sequestration

"Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies"

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