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As the concentration of added AMG 966 is increased, eventually the exogenous AMG 966 will directly compete with Ru-AMG 966 for binding to TNF and/or TL1A, causing signal to decrease

[DOI] [PubMed] [Google Scholar] 105.Majzoub A., Agarwal A

This compact size contributes to reduced steric hindrance and increased flexibility

Citation: Johansen, P
2D Spectral Cross-Correlation has been employed to similarly differentiate between drug binding events and cellular response pathways (Farhane et al., 2018b), and Spectral Cross-Correlation in cellular maps has been demonstrated as a sensitive tool to profile the subcellular distribution of specific spectral signatures (Keating et al., 2012)

doi: 10.1016/j.ejps.2020.105316 [DOI] [PubMed] [Google Scholar] 144.Yuan L, Zhao J, Sun T, et al
