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It Helps Lower Blood Sugar and Improve Insulin Resistance A 2023 review of 41 clinical trials (involving nearly 2,900 people) found that taking L-Carnitine helped: Lower fasting blood sugar Improve insulin sensitivity (HOMA-IR) Reduce HbA1c levels (a long-term marker of blood sugar control) These effects were strongest in people with type 2 diabetes , obesity , fatty liver , or PCOS (Polycystic Ovary Syndrome)

Sgambat K, Frank L, Ellini A, Sable C, Moudgil A (2012) Carnitine supplementation improves cardiac strain rate in children on chronic hemodialysis

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C57BL/6J mice were housed at 27C in a controlled environment with a 12-h/12-h light/dark cycle, with free access to water and a high-cholesterol diet (HCD