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1 Aged Muscle Stem Cell Rejuvenation Neelakantan et al., Biochemical Pharmacology (2019) In a follow-up study, the authors tested whether NNMT inhibition could reverse the age-related decline in muscle stem cell (satellite cell) function

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Restoring NAD + levels with dietary precursors and targeting NAD + degradation enzymes with small-molecule inhibitors has emerged as a potential therapeutic strategy to restore NAD + levels, thereby providing opportunities for alleviating age-related decline and diseases (FIG