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Description
Inflammation connects to ED through endothelial dysfunction and neural sensitization, as chronic inflammatory signaling through NF-kappaB and JAK-STAT pathways can damage the vascular reactivity required for erection

Magnesium directly inhibits the NF-kappaB (nuclear factor kappa-light-chain-enhancer of activated B cells) inflammatory signalling pathway

10.1016/0024-3205(79)90093-6 21.Hamilton MG , Blum K , Hirst M

NAD+ boosts energy, clarity, and emotional resilience, which is especially helpful during high-stress seasons or post-burnout recovery

Glutathione (-glutamyl-cysteinylglycine) is a major intracellular antioxidant and plays a key role in reducing the effects of oxidative stress [10, 11]

However, rather than using anti-oxidant treatment, an adequate approach would involve acting on lifestyles [22], such as by reducing health-risk behaviors such as alcohol or smoking [134,215], by improving physical exercise [216], or when risk cannot be avoided, by enacting strategies aimed at harm reduction [125]
