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(29) indicated that the average relative intensity of propionylcarnitine (C3:0), and butyrylcarnitine (C4:0) in plasma of overtired and depressed rats was lower than that of healthy control group

Jones, 2010)

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This non-essential amino acid plays a part in the body's ability to metabolize long-chain fatty acids

Assembly of the L-Carnitine Biosynthetic Pathway After efficient enzymes for the last and penultimate step of the L-carnitine biosynthetic pathway had been identified, enzymes for the first two steps were selected: TML hydroxylase and an HTML aldolase (Supplementary Table 1)