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Used in research planning when more precise dose control is wanted

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Karsdal MA, Byrjalsen I, Alexandersen P, et al

Petraschka M, Li S, Gilbert TL, Westenbroek RE, Bruchas MR, Schreiber S, Lowe J, Low MJ, Pintar JE, Chavkin C: The absence of endogenous beta-endorphin selectively blocks phosphorylation and desensitization of mu opioid receptors following partial sciatic nerve ligation

The in vivo study utilized naturally aged male C57BL/6 mice between 20-24 months old and young adult male C57BL/6 mice that were 3 months old