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We have shown for the first time that stable deletion of GSTP1 in A2780 ovarian tumour cells significantly and selectively increases sensitivity to cisplatin and carboplatin, drugs routinely used to treat ovarian cancer, a notoriously drug-resistant and clinically intractable disease

Factors That May Affect Appropriateness According to general clinical guidance referenced in published sources, growth hormone secretagogues may not be appropriate for individuals with certain contraindications including active malignancies, uncontrolled diabetes, or other conditions that a clinician would evaluate during the prescribing process

However, for those with specific respiratory concerns, the question of whether to supplement requires a more nuanced look at delivery methods and biological impact

Cureus , 16(9), e70279.

doi: 10.1016/j.envint.2022.107173

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