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87 Aspartate in cancer TP53 is a gene with the highest mutation frequency in human cancer

Landscapes Health & Medical Sciences (AREA) Chemical & Material Sciences (AREA) Medicinal Chemistry (AREA) Pharmacology & Pharmacy (AREA) Epidemiology (AREA) Life Sciences & Earth Sciences (AREA) Animal Behavior & Ethology (AREA) General Health & Medical Sciences (AREA) Public Health (AREA) Veterinary Medicine (AREA) Medicinal Preparation (AREA) Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA) Abstract An improved method for delivery of glutathione, a major intracellular antioxidant, by oral administration of S-acetyl-glutathione (SAG) is provided

Taken together, the above considerations regarding the prevalence and clinical correlates of HT highlight this disease as an area of unmet medical need with broad relevance for public health

It achieves this effect through three unique pathways: Glutathione is a tripeptide compound synthesized from the amino acids glutamine, glycine and cysteine