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In our study, we systematically demonstrated that ACTL6A inhibited GC cell ferroptosis by promoting GSH synthesis through upregulating GCLC

Score based on the proportion of positive cells: (1) 1 point, 50% of cells stained positively (Fig

Under oxidative stress conditions, ROS or electrophiles interact with or modify KEAP1 cysteine (Cys) residues, resulting in conformational changes in the KEAP1 protein and subsequent disruption of the NRF2 DLG motif-KEAP1CUL3 complex

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Several issues remain to be addressed

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