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PRPF6 promotes ovarian cancer metastasis and paclitaxel resistance by inducing alternative splicing of SNHG16 (downregulating SNHG16-L while upregulating SNHG16-S), where SNHG16-L inhibits GATA3 transcription through CEBPB binding, ultimately forming a PRPF6/SNHG16-L/CEBPB/GATA3 regulatory axis, with clinical correlations showing PRPF6 overexpression in chemoresistant OC tissues linked to advanced FIGO stages and poor therapeutic outcomes [114]

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Comparison to published data To compare our human HRMS lipid intensity dataset to published mouse brain lipidome atlas data 21 and murine cell type-specific primary culture lipid data 20 , we downloaded the original published raw intensities and preprocessed them using our human HRMS data processing pipeline with no modifications

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