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NAD+ (nicotinamide adenine dinucleotide) is a crucial coenzyme found in every cell in the body

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In patients with acute neurologic manifestations of Lyme disease, such as those presenting with Lyme-associated meningitis, cranial neuropathy, radiculoneuropathy, or other peripheral nervous system manifestations, IV ceftriaxone, cefotaxime, penicillin G, or oral doxycycline are recommended as preferred therapy ( TABLE 1 )

Tolerant or sensitive species exhibit differential stress tolerance, depending on the level of accumulation of these compounds during abiotic stress (Obata and Fernie, 2012)