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All these metabolites would be directly or indirectly excreted back to the lumen or be excreted via the bile

The conceptpreparation and observation to avoid catastrophic eventsis familiar in construction, where safety programs rely on prevention through policies, accountability, and training

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Maintenance doses are given less often than initial doses

We investigate a particular aspect of the sudden onset of encephalopathy with paracetamol overdose (for review see 1-3) so far not reported: may paracetamol rapidly induce hepatic encephalopathy with generalized convulsions in rats and if so, the possible therapy effect in early and advanced stage

There is probably a lacking variable in the elderly that makes them more vulnerable to the severity of disease
