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Description
SS-31: Protects mitochondria from ROS-mediated injury

Generated through a P450 cytochrome-oxidative pathway, NAPQI is normally inactivated by glutathione (GSH) conjugation, forming the 3-glutathionyl-S-yl-APAP adduct (3-GS-APAP)

These metabolic axes take part in shaping the ferroptosis-susceptible cell-state collectively, and the relative contribution of each axis is likely dictated by the cellular contexts and by the specific ferroptosis-inducing approaches (Fig

Pregnancy/Nursing: Neonates exposed to antipsychotic drugs, including ARISTADA INITIO and ARISTADA, during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms

1992;15(9 Suppl 6):1217

[DOI] [PubMed] [Google Scholar] 162.McAllister AK, van de Water J
