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Class B GPCRs (e.g., AT 1A R, NK 1 R, PAR 2 ) exhibit stronger and more stable binding to -Arr at plasma and endosomal membranes than class A receptors
The ER also maintains redox homeostasis, crucial for ferroptosis regulation (68)

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11,13,80,82,83 White adipose tissue in individuals with obesity is expanded and infiltrated with T cells, bone-marrow-derived macrophages, mast cells and B cells

Additionally, it was emphasized that dietary intervention may have negative effects on gastrointestinal symptoms [36]