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Effects of natural polyphenols on the expression of drug efflux transporter P-glycoprotein in human intestinal cells

824 The relationship between drug resistance to epigenetic agents and mutations in certain genes is observed in tumor cells, especially in the case of applying EZH2 and IDH inhibitors

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It has been proposed that the SNX27 FERM domain directly binds to SNX2, and that this interaction is required to transfer the cargo proteins to the ESCPE-1 transport carrier to facilitate endosome-to-plasma membrane recycling 37