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showed that ARID1A-deficient cancer cells expressed low levels of the key cystine transporter SLC7A11 and thus exhibited low basal levels of GSH, which made these cancer cells specifically vulnerable to inhibition of the GSH metabolic pathway 25

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Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8 + T cell metabolic fitness and function in tumors

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10.1016/j.molcel.2018.07.015 32 CaseroR

They also suggest that etomidate may have antidepressant effects by increasing BDNF, thereby protecting hippocampal neurons from ferroptosis (Li X
