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(2024a)
J.JiaJ.NixonA
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They emphasized that HO-1 functions as an oxidative agonist rather than a driver of ferroptosis, and that ferroptosis occurs only as a secondary event following severe oxidative damage (155)

As known, ROS are free radicals and/or oxygen derivatives that include superoxide anion, hydrogen peroxide, hydroxyl radical, lipid hydroperoxides, peroxyl radicals, and peroxynitrite

Functional foods and bioactive compounds: A comprehensive review on their role in mitigating drug-induced liver injury
