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Reactive oxygen species and sperm cells

Arsenic may directly induce atherosclerosis by increasing the mRNA transcription of growth factors such as granulocyte-macrophage colony stimulating factor (GMCSF) and TGF, and inflammatory cytokines such as TNF- and IL-6 ( Protective Effects of Natural Products Against Environmental Toxins-Induced Cardiotoxicity Cadmium-Induced Cardiotoxicity Heavy mental Cadmium (Cd), a ubiquitous environmental pollutant, was listed as the first category human carcinogen by the International Agency for Research on Cancer (IARC) in 1993

Additionally, IGFs can bind both the IGF-1R and the IR due to structural homology between the receptors [156,157,158]

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So the long way, and I'm not against this at all

10.3390/ijms21176091 5 AyobA