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4 Cellular and molecular aging interventions 4.1 Epitalon: targeting telomere biology Telomere attrition ranks among the most fundamental hallmarks of aging

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This peripheral inflammation is a known driver of neuroinflammation, which is implicated in mood disorders, cognitive decline, and neurodegenerative diseases

5.1 Probiotics, prebiotics, and synbiotics Probiotics, prebiotics, and synbiotics, as core interventions targeting the gut microbiota-ENS axis, exhibit tremendous potential in repairing neural damage and improving motility disorders in DGE by reshaping microbial structure and metabolic profiles (as detailed in Tables 1 , 2 )

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Fertility goals, baseline health conditions, medications, and psychological state all impact whether any experimental treatment would be considered