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105 In this context, therapeutic strategies aimed at enhancing the normal tolerogenic liver mechanisms that lead to the resolution of inflammation, fibrosis regression and hepatocyte regeneration, may augment the existing immunosuppressive treatments

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Electrostatic forces are described by the function representing the expression for the Coulomb interaction: where is the permittivity, Q 1 and Q 2 are charges on the interacting atoms, and d is the interatomic distance

414 Additionally, Catechol-containing polyphenols induce ROS via tyrosinase-mediated oxidation, triggering ASK1/JNK/p38 signaling and apoptosis in A375 melanoma cells

Environmental insults such as cigarette smoke or bacterial endotoxins (e.g., LPS), as well as intrinsic triggers including DAMPs released from stressed or dying epithelial cells, can engage TLR4 receptors on AECs (85)

Theranostics 11(5):23812394 Stampar M et al (2021) Hepatocellular carcinoma (HepG2/C3A) cell-based 3D model for genotoxicity testing of chemicals