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To our knowledge, dogs with naturally occurring IVD degeneration have not been used, even though it is recognized that CD dog breeds are a suitable animal model of spontaneous IVD degeneration [9, 13]

In the normal tissues, a large number of red-stained chondrocytes and cell stroma were observed in the NP, while a significant reduction was found in patients who underwent PELD

24,65 However, Schmorls nodes may have different aetiologies, and cause-response in relation to disc degeneration remains a question of debate

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