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Discovery of 2-vinyl-10H-phenothiazine derivatives as a class of ferroptosis inhibitors with minimal human Ether-a-go-go related gene (hERG) activity for the treatment of DOX-induced cardiomyopathy
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In vivo studies showed a tumor inhibition rate of 53.99%, higher than the parent inhibitor AT13387 (43%), with reduced toxicity
Howitz, K
The area was washed with betadine followed by 70% ethanol and then draped
