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The genomic study of SARS-CoV-2 has explored about 79% resemblance with SARS-CoV which became epidemic in 2002 [4]
Hoskin DW, Ramamoorthy A
doi:10.1016/j.bcp.2023.115767 131
While more is known about the transporters that handle Mn uptake into enterocytes, less is understood about which transporter exports Mn from enterocytes into the bloodstream on the basolateral membrane
Additionally, elevated plasma choline acetyltransferase (ChAT) concentrations were observed in patients with sepsis, with the highest levels detected in those who succumbed to infection (252)
Perhaps this has to do with the specific discrete mutational event causing their development
