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After a bolus dose of 250 mg/kg in 90120 min, the maintenance dose is 250500 mg/kg/day given in continuous infusion.27 Sodium phenylacetate or sodium phenylbutyrate binds with glutamine to produce phenylacetylglutamine which is also eliminated in urine

These triggers all interact with the immune system and may leave a stuck danger signal even when the infection is no longer obvious