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However, a trend toward higher GSH in drug-free patients raises the possibility of long-term antipsychotic effects on antioxidant systems, consistent with preclinical studies showing certain antipsychotics enhance antioxidant defenses via BDNF and ERK/Akt pathway activation (35)

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Li Y, Zafar S, Salih Ibrahim RM, Chi H-L, Xiao T, Xia W, Li H-B, Kang Y-M