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Huang PS, Wang CS, Yeh CT, Lin KH (2019) Roles of thyroid hormone-associated microRNAs affecting oxidative stress in human hepatocellular carcinoma

4855 min, 99% MPB

In vivo characterization has empirically confirmed this spatial restriction, showing that the AND gate circuit tightly restricts expression of the therapeutic gene to the TME and remains off in healthy organs, leading to a dramatic decrease in off-target toxicity

In particular, it has long been established that the thiol moiety of GSH is important in its antioxidant function in the direct scavenge of radical species

11 BellingerF

Protein oxidation is another critical molecular mechanism by which oxidative stress impairs sperm function