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Additionally, some studies have proposed or demonstrated the underlying mechanisms or therapeutic targets related to PCC development and where cannabis, or its metabolites, could interact

Animal Model:Hyperreactive rats (male and female, 200-400 g, pretreated intravenously with 3 g/kg methysergide, 5 min before antigen chdlenge) [1] Dosage:0.5, 0.15, and 0.05 mg/kg Administration:Orally, once, 1 or 4 h before challenge Result:Produced dose-dependent inhibition of the duration of antigen-induced dyspnea, with ED 50 values of 0.13 (95% confidence interval (CI), 0.03-0.62) and 0.11 (95% CI, 0.009-1.47) mg/kg, respectively

Geeraerts SL, Heylen E, De Keersmaecker K, Kampen KR

Overall, theyre quite safe

There are three distinct assumptions made here

Below is a breakdown of rare but serious warnings and precautions to consider with tirzepatide