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Overexpression of tiRNA-Glu-CTC in VSMCs promoted a shift from the contractile to the synthetic phenotype, characterized by downregulation of the contractile markers -SMA, SM22, and SMMHC and upregulation of the synthetic markers collagen I and vimentin, an effect regulated through its target Cacna1f [20]

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Cells 12, (2023), Abstract Discovery of a novel dual functional phenylpyrazole-styryl hybrid that induces apoptotic and autophagic cell death in bladder cancer cells: S.W