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Elife 8 , e48167 (2019)

Synthesis of triglycerides occurs in most cells but predominantly occurs in intestinal enterocytes for the delivery of dietary fatty acids to the body and hepatocytes of the liver for the delivery of endogenous fatty acids to, primarily, cardiac and skeletal muscle, and to adipocytes

Some studies of semaglutide have also shown cardiovascular benefit in certain high-risk patients, although treatment decisions should always be individualized

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In contrast, monoglycerides and fatty acids with longer chains undergo reassembly into triglycerides within the cells of the small intestine [15]