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185 Besides, ROS-driven JAK/STAT signaling upregulates Z-DNA binding protein 1 (ZBP1), which forms a complex with RIPK3 in the absence of RIPK1, triggering MLKL-mediated necroptosis

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Injection sites must also be rotated to prevent irritation and lipodystrophy, which causes fatty lumps on the body

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Hepatology 59, 11071117

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Blood samples were obtained from 116 children hospitalised at the Department of Paediatric Haematology and Oncology (Faculty Hospital Motol, Prague, Czech Republic) with newly diagnosed solid tumours of neuroblastoma (n=27), nephroblastoma (n=8), anaplastic ependymoma (n=4), Ewings sarcoma (n=9), germ cell tumour (n=4), osteosarcoma (n=16), tumour of the genital tract (n=6), Hodgkins lymphoma (n=16), lymphadenopathy (n=3), medulloblastoma (n=15), rhabdomyosarcoma (n=4) and retinoblastoma (n=4)

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