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pneumoniae infection, the peripheral blood CD4+ T count is decreased, however, the ratio of T-lymphocytes to CD4+/CD8+ cells in the bronchoalveolar lavage fluid increases, possibly due to abundant CD4+ T cells being involved in the inflammatory reaction (54)

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Increased apoptotic cell death is a frequent outcome, as evidenced by the upregulation of markers like caspases and the BAX/Bcl-2 ratio

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(London, UK: The Royal Society of Chemistry), 11, 151164