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While comprehensive cost-effectiveness analyses are limited, silymarin is often considered an economically viable option due to its availability and relatively low cost compared to some pharmaceutical treatments

Fumarate is a terminal electron acceptor in the mammalian electron transport chain

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Yes many counterfeit formulations contain free copper ions from copper sulfate or copper chloride, which can cause oxidative stress, inflammation, and contact dermatitis when applied topically at concentrations above 0.5%

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Acta Ophthalmol (Copenh) 1986;64:298301